VX-809, CAS 936727-05-8

  • VX-809, CAS 936727-05-8

VX-809, CAS 936727-05-8
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 936727-05-8
  • Stock: 899g
  • Assay: 98.54%

VX-809, CAS 936727-05-8

VX-809, CAS 936727-05-8Stock 899g, Assay 98.54%, White powderWater 0.26%, Single Impurity 0.34%.


Lumacaftor, also known as VX-809, is a potent CFTR corrector, many be useful for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation. Cystic fibrosis (CF) is a genetic disorder that causes multiorgan morbidity and premature death, most commonly from pulmonary dysfunction.

Product Details:

Name: Lumacaftor

CAS#: 936727-05-8

Chemical Formula: C24H18F2N2O5

Exact Mass: 452.11838

Molecular Weight: 452.41

Elemental Analysis: C, 63.72; H, 4.01; F, 8.40; N, 6.19; O, 17.68


Synonym: VX-809; VX809; VX 809; VRT-826809; VRT 826809; VRT826809; Lumacaftor; Orkambi;

IUPAC/Chemical Name: 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid


InChi Code: InChI=1S/C24H18F2N2O5/c1-13-5-8-19(27-20(13)14-3-2-4-15(11-14)21(29)30)28-22(31)23(9-10-23)16-6-7-17-18(12-16)33-24(25,26)32-17/h2-8,11-12H,9-10H2,1H3,(H,29,30)(H,27,28,31)

SMILES Code: O=C(O)C1=CC=CC(C2=NC(NC(C3(C4=CC=C(OC(F)(F)O5)C5=C4)CC3)=O)=CC=C2C)=C1

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001