Golvatinib, CAS 928037-13-2

  • Golvatinib, CAS 928037-13-2

Golvatinib, CAS 928037-13-2
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 928037-13-2
  • Stock: 896g
  • Assay: 98.66%

Golvatinib, CAS 928037-13-2

Golvatinib, CAS 928037-13-2Stock 896g, Assay 98.66%, White powderWater 0.35%, Single Impurity 0.32%.


Golvatinib, also known as E7050, is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of various tumor cell types and play important roles in tumor cell growth, migration and angiogenesis.

Product Details:

Name: Golvatinib

CAS#: 928037-13-2

Chemical Formula: C33H37F2N7O4

Exact Mass: 633.28751

Molecular Weight: 633.69

Elemental Analysis: C, 62.55; H, 5.89; F, 6.00; N, 15.47; O, 10.10


Synonym: E7050; E-7050; E 7050; Golvatinib.

IUPAC/Chemical Name: N-(2-fluoro-4-((2-(4-(4-methylpiperazin-1-yl)piperidine-1-carboxamido)pyridin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide


InChi Code: InChI=1S/C33H37F2N7O4/c1-39-16-18-40(19-17-39)23-9-14-41(15-10-23)32(45)38-29-21-26(8-13-37-29)46-25-6-7-28(27(35)20-25)42(24-4-2-22(34)3-5-24)31(44)33(11-12-33)30(36)43/h2-8,13,20-21,23H,9-12,14-19H2,1H3,(H2,36,43)(H,37,38,45)


Appearance: white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001