CAS 898800-26-5: AZ-876
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AZ-876, CAS 898800-26-5

AZ-876, CAS 898800-26-5, Stock 1593g, Assay 98.71%, White powder, Water 0.56%, Single Impurity 0.14%.

AZ-876

AZ876, also known as AZ-876, is a liver X receptor agonist. AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects. LXR activation with AZ876 attenuated this increase, and significantly reduced TAC-induced increases in heart weight, myocardial fibrosis, and cardiac dysfunction without affecting blood pressure. Liver X receptors (LXRs) transcriptionally regulate inflammation, metabolism, and immunity.

Product Details:

Name: AZ876

CAS#: 898800-26-5

Chemical Formula: C24H29N3O3S

Exact Mass: 439.193

Molecular Weight: 439.574

Elemental Analysis: C, 65.58; H, 6.65; N, 9.56; O, 10.92; S, 7.29

Specification:

Synonym: AZ876; AZ 876; AZ-876, AZ12260493; AZ 12260493; AZ-12260493.

IUPAC/Chemical Name: 2-(1,1-Dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-3(2H)-isothiazolone 1,1-dioxide

InChi Key: IVANYIPLGFVBGR-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H29N3O3S/c1-24(2,3)27-23(28)21(22(31(27,29)30)18-10-6-4-7-11-18)25-19-12-14-20(15-13-19)26-16-8-5-9-17-26/h4,6-7,10-15,25H,5,8-9,16-17H2,1-3H3

SMILES Code: O=C(C(NC1=CC=C(N2CCCCC2)C=C1)=C3C4=CC=CC=C4)N(C(C)(C)C)S3(=O)=O

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: