Lesinurad（Rdea594), CAS 878672-00-5
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CAS Number: 878672-00-5
Stock: 876g
Assay: 98.63%

Lesinurad（Rdea594), CAS 878672-00-5

Lesinurad（Rdea594), CAS 878672-00-5, Stock 876g, Assay 98.63%, White powder, Water 0.26%, Single Impurity 0.32%.

RDEA594

Lesinurad, also known as RDEA594, is a selective uric acid re-absorption inhibitor (SURI) and is also a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. RDEA594 has been shown to normalize the amount of uric acid excreted by gout patients previously classified as under-excretors. Lesinurad received FDA approval on December 22, 2015.

Product Details:

Name: Lesinurad free acid
CAS#: 878672-00-5 (free acid)
Chemical Formula: C17H14BrN3O2S
Exact Mass: 402.999
Molecular Weight: 404.28
Elemental Analysis: C, 50.51; H, 3.49; Br, 19.76; N, 10.39; O, 7.91; S, 7.93

Specification:

Related CAS #: 1151516-14-1 (sodium) 878672-00-5 (free acid)
Synonym: Lesinurad; RDEA594; RDEA 594; RDEAi594; Zurampic;
IUPAC/Chemical Name: 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid
InChi Key: FGQFOYHRJSUHMR-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)
SMILES Code: O=C(O)CSC1=NN=C(Br)N1C2=C3C=CC=CC3=C(C4CC4)C=C2
Appearance: white powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001