Omecamtiv Mecarbil, CAS 873697-71-3

  • Omecamtiv Mecarbil, CAS 873697-71-3

Omecamtiv Mecarbil, CAS 873697-71-3
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 873697-71-3
  • Stock: 697g
  • Assay: 98.67%

Omecamtiv Mecarbil, CAS 873697-71-3

Omecamtiv Mecarbil, CAS 873697-71-3Stock 897g, Assay 98.67%, White powderWater 0.24%, Single Impurity 0.32%.


CK-1827452

Omecamtiv mecarbil, also known as CK-1827452, is a cardiac specific myosin activator. It is clinically tested for its role in the treatment of left ventricular systolic heart failure. Omecamtiv Mecarbil specifically targets and activates myocardial ATPase and improves energy utilization. Omecamtiv Mecarbil improves systolic function by increasing the systolic ejection duration/stroke volume, without consuming more ATP energy, oxygen or altering intracellular calcium levels causing an overall improvement in cardiac efficiency. (source: http://en.wikipedia.org/wiki/Omecamtiv_mecarbil)


Product Details:

Name: Omecamtiv mecarbil

CAS#: 873697-71-3

Chemical Formula: C20H24FN5O3

Exact Mass: 401.1863

Molecular Weight: 401.43

Elemental Analysis: C, 59.84; H, 6.03; F, 4.73; N, 17.45; O, 11.96


Specification:

Synonym: Omecamtiv mecarbil; CK1827452; CK 1827452; CK1827452.

IUPAC/Chemical Name: methyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate

InChi Key: RFUBTTPMWSKEIW-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H24FN5O3/c1-14-6-7-16(12-22-14)23-19(27)24-17-5-3-4-15(18(17)21)13-25-8-10-26(11-9-25)20(28)29-2/h3-7,12H,8-11,13H2,1-2H3,(H2,23,24,27)

SMILES Code: O=C(N1CCN(CC2=CC=CC(NC(NC3=CC=C(C)N=C3)=O)=C2F)CC1)OC

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certification: