EX-527(R), CAS 848193-69-1

  • EX-527(R), CAS 848193-69-1

EX-527(R), CAS 848193-69-1
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  • CAS Number: 848193-69-1
  • Stock: 781g
  • Assay: 98.64%

EX-527(R), CAS 848193-69-1

EX-527(R), CAS 848193-69-1Stock 781g, Assay 98.64%, White powderWater 0.24%, Single Impurity 0.32%.


(R)-Selisistat, also known as EX-527(R), is a selective SIRT1 inhibitor. Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases.

Product Details:

Name: (R)-Selisistat

CAS#: 848193-69-1 (R-isomer)

Chemical Formula: C13H13ClN2O

Exact Mass: 248.0716

Molecular Weight: 248.71

Elemental Analysis: C, 62.78; H, 5.27; Cl, 14.25; N, 11.26; O, 6.43


Related CAS #: 848193-69-1 (R-isomer)   848193-68-0 (S-isomer)   49843-98-3 (racemate)    

Synonym: (R)-Selisistat; EX-527(R); EX 527(R); EX527(R);

IUPAC/Chemical Name: (R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide


InChi Code: InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m1/s1

SMILES Code: O=C([C@H]1C(NC2=C3C=C(Cl)C=C2)=C3CCC1)N

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001