KW-2478, CAS 819812-04-9

  • KW-2478, CAS 819812-04-9

KW-2478, CAS 819812-04-9
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 819812-04-9
  • Stock: 798g
  • Assay: 98.83%

KW-2478, CAS 819812-04-9

KW-2478, CAS 819812-04-9Stock 798g, Assay 98.83%, White powderWater 0.39%, Single Impurity 0.38%.


KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be fully elucidated, Hsp90 antagonist KW-2478 appears to inhibit Hsp90, resulting in impaired signal transduction, inhibition of cell proliferation, and the induction of apoptosis in tumor cells.

Product Details:

Name: KW-2478 free base

CAS#: 819812-04-9 (free base)

Chemical Formula: C30H42N2O9

Exact Mass: 574.28903

Molecular Weight: 574.66248

Elemental Analysis: C, 62.70; H, 7.37; N, 4.87; O, 25.06


Related CAS #: 819812-18-5 (HCl)   819812-04-9 (free base)    

Synonym: KW2478; KW-2478; KW 2478.

IUPAC/Chemical Name: 2-(2-ethyl-3,5-dihydroxy-6-(3-methoxy-4-(2-morpholinoethoxy)benzoyl)phenyl)-N,N-bis(2-methoxyethyl)acetamide


InChi Code: InChI=1S/C30H42N2O9/c1-5-22-23(19-28(35)32(11-13-37-2)12-14-38-3)29(25(34)20-24(22)33)30(36)21-6-7-26(27(18-21)39-4)41-17-10-31-8-15-40-16-9-31/h6-7,18,20,33-34H,5,8-17,19H2,1-4H3


Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)

Solubility: Soluble in DMSO, not soluble in water.

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001