Luminespib(NVP-AUY922), CAS 747412-49-3

  • Luminespib(NVP-AUY922), CAS 747412-49-3

Luminespib(NVP-AUY922), CAS 747412-49-3
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 747412-49-3
  • Stock: 754g
  • Assay: 98.26%

Luminespib(NVP-AUY922), CAS 747412-49-3

Luminespib(NVP-AUY922), CAS 747412-49-3, Stock 754g, Assay 98.26%, White powderWater 0.23%, Single Impurity 0.64%.


Luminespib, also known as AUY-922, NVP-AUY922, VER52296, is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines.

Product Details:

Name: Luminespib (AUY-922 )

CAS#: 747412-49-3

Chemical Formula: C26H31N3O5

Exact Mass: 465.22637

Molecular Weight: 465.54

Elemental Analysis: C, 67.08; H, 6.71; N, 9.03; O, 17.18


Synonym: AUY922; AUY-922; AUY 922; NVP AUY922; NVP AUY-922; VER52296 ; VER-52296 ; VER 52296 ; Luminespib

IUPAC/Chemical Name: 5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide


InChi Code: InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)


Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001