Mephenytoin, CAS 50-12-4

  • Mephenytoin, CAS 50-12-4

Mephenytoin, CAS 50-12-4
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  • CAS Number: 50-12-4
  • Stock: 1.76kg
  • Assay: 98.71%

Mephenytoin, CAS 50-12-4

Mephenytoin, CAS 50-12-4, Stock 1764g, Assay 98.71%, White powderWater 0.52%, Single Impurity 0.18%.


Mephenytoin (racemic) is a hydantoin, used as an anticonvulsant. It was introduced approximately 10 years after phenytoin, in the late 1940s. The significant metabolite of mephenytoin is nirvanol (5-ethyl-5-phenylhydantoin), which was the first hydantoin (briefly used as a hypnotic). However, nirvanol is quite toxic and mephenytoin was only considered after other less toxic anticonvulsants had failed. It can cause potentially fatal blood dyscrasia in 1% of patients. Mephenytoin is no longer available in the US or the UK. It is still studied largely because of its interesting hydroxylation polymorphism.

Product Details:

Name: Mephenytoin

CAS#: 50-12-4 (racemic)

Chemical Formula: C12H14N2O2

Exact Mass: 218.10553

Molecular Weight: 218.25

Elemental Analysis: C, 66.04; H, 6.47; N, 12.84; O, 14.66


Synonym: Mephenytoin; Methoin; Mesantoin; Phenantoin; Methylphenetoin; Insulton.

IUPAC/Chemical Name: 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione


InChi Code: InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)

SMILES Code: CCC1(C(=O)N(C(=O)N1)C)C2=CC=CC=C2

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001