Cenicriviroc, CAS 497223-25-3

  • Cenicriviroc, CAS 497223-25-3

Cenicriviroc, CAS 497223-25-3
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 497223-25-3
  • Stock: 552g
  • Assay: 98.36%

Cenicriviroc, CAS 497223-25-3

Cenicriviroc, CAS 497223-25-3, Stock 552g, Assay 98.36%, White powder, Water 0.41%, Single Impurity 0.18%.


Cenicriviroc

Cenicriviroc, also known as TAK-652 and TBR-652, is an experimental drug candidate for the treatment of HIV infection. It is being developed by Takeda Pharmaceutical and Tobira Therapeutics. Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell. Inhibition of CCR2 may have an anti-inflammatory effect.


Product Details:

Name: Cenicriviroc

CAS#: 497223-25-3 (free base)

Chemical Formula: C41H52N4O4S

Exact Mass: 696.37093

Molecular Weight: 696.95

Elemental Analysis: C, 70.66; H, 7.52; N, 8.04; O, 9.18; S, 4.60


Specification:

Synonym: TAK-652; TAK652; TAK 652; TBR-652; TBR 652; TBR652; Cenicriviroc.

IUPAC/Chemical Name: (S,E)-8-(4-(2-Butoxyethoxy)phenyl)-1-isobutyl-N-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydrobenzo[b]azocine-5-carboxamide

InChi Key: PNDKCRDVVKJPKG-WHERJAGFSA-N

InChi Code: InChI=1S/C41H52N4O4S/c1-5-7-22-48-23-24-49-38-15-10-32(11-16-38)33-12-19-40-35(25-33)26-34(9-8-21-44(40)28-31(3)4)41(46)43-36-13-17-39(18-14-36)50(47)29-37-27-42-30-45(37)20-6-2/h10-19,25-27,30-31H,5-9,20-24,28-29H2,1-4H3,(H,43,46)/b34-26+/t50-/m0/s1

SMILES Code: O=C(/C1=C/C2=CC(C3=CC=C(OCCOCCCC)C=C3)=CC=C2N(CC(C)C)CCC1)NC4=CC=C([S@](CC5=CN=CN5CCC)=O)C=C4

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: