CAS 36085-73-1: Talipexole HCl

  • CAS 36085-73-1: Talipexole HCl

CAS 36085-73-1: Talipexole HCl
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  • CAS Number: 36085-73-1
  • Stock: 103g
  • Assay: 99.70%

Talipexole HCl, CAS 36085-73-1

Talipexole HCl, CAS 36085-73-1, Stock 103g, Assay 99.7%, White powder, Water 0.34%, Single Impurity 0.3%.

Talipexole HCl

Talipexole, also known as B-HT920 and Domnin, is a dopamine agonist that is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe. Talipexole is a D2 dopamine receptor agonist and interacts both pre- and post-synaptic receptors. It also is an α2-adrenergic agonist. The main side effects are drowsiness, dizziness, hallucinations and minor gastrointestinal complaints. In 2008 the Japanese Ministry of Health, Labour, and Welfare mandated that Boehringer add a warning to the label concerning the risk of sudden onset of sleep.

Product Details:

Name: Talipexole HCl

CAS#: 36085-73-1 (2HCl)

Chemical Formula: C10H17Cl2N3S

Exact Mass:

Molecular Weight: 282.227

Elemental Analysis: C, 42.56; H, 6.07; Cl, 25.12; N, 14.89; S, 11.36


Synonym: B-HT 920, B-HT-920, B-HT920, Talipexole HCl, Talipexole dihydrochloride, Domnin

IUPAC/Chemical Name: 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo(4,5-d)azepine dihydrochloride


InChi Code: InChI=1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8;;/h2H,1,3-7H2,(H2,11,12);2*1H

SMILES Code: NC(S1)=NC2=C1CCN(CC=C)CC2.[H]Cl.[H]Cl

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001