CAS 289893-26-1: Arimoclomol maleate
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Arimoclomol maleate, CAS 289893-26-1

Arimoclomol maleate, CAS 289893-26-1, Stock 1382g, Assay 98.36%, White powder, Water 0.15%, Single Impurity 0.27%.

Arimoclomol maleate

 Arimoclomol, also known as BRX-220, is a heat shock protein amplifier, and is potentially useful for the treatment of Niemann-Pick disease type C (NP-C). Arimoclomol is believed to function by stimulating a normal cellular protein repair pathway through the activation of molecular chaperones. Arimoclomol could treat a broad range of diseases. Arimoclomol activates the heat shock response. It is believed to act at Hsp70.

Product Details:

Name: Arimoclomol maleate

CAS#: 289893-26-1 (maleate)

Chemical Formula: C18H24ClN3O7

Exact Mass: 429.1303

Molecular Weight: 429.854

Elemental Analysis: C, 50.30; H, 5.63; Cl, 8.25; N, 9.78; O, 26.05

Specification:

Synonym: Arimoclomol maleate; BRX-220; BRX 220; BRX220; BRX-345; BRX 345; BRX345.

IUPAC/Chemical Name: (R,Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide maleate

InChi Key: OHUSJUJCPWMZKR-GARNONDBSA-N

InChi Code: InChI=1S/C14H20ClN3O3.C4H4O4/c15-14(12-5-4-8-18(20)9-12)16-21-11-13(19)10-17-6-2-1-3-7-17;5-3(6)1-2-4(7)8/h4-5,8-9,13,19H,1-3,6-7,10-11H2;1-2H,(H,5,6)(H,7,8)/b16-14-;2-1-/t13-;/m1./s1

SMILES Code: Cl/C(C1=C[N+]([O-])=CC=C1)=N\OC[C@H](O)CN2CCCCC2.O=C(O)/C=C\C(O)=O

Appearance: White powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: