CAS 2516-47-4 | AVOR-005 : Avoralstat
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CAS 2516-47-4 is a chemical compound with the molecular formula C8H8N2O2. It is also known as 2,4-dinitrophenylhydrazine (DNPH) and is commonly used as a reagent for the detection and quantification of carbonyl compounds in organic chemistry.

Chemical Properties

CAS 2516-47-4 is a yellow to orange crystalline powder that is soluble in ethanol, acetone, and ether. It has a melting point of 170-173°C and a boiling point of 250°C. DNPH is highly reactive towards carbonyl compounds, forming a bright yellow to orange precipitate that can be used for identification and quantification. It is also sensitive to light and can decompose if exposed to prolonged light exposure.

Applications

DNPH is commonly used in the field of analytical chemistry for the detection and quantification of carbonyl compounds. It is used as a reagent in tests such as the Brady's test, which is used to detect the presence of aldehydes and ketones in a sample. It is also used in the Hantzsch reaction, which is used to synthesize pyridine derivatives.

In addition to its use in analytical chemistry, DNPH has also been used as a component in explosives and as a pesticide. However, due to its toxicity and potential health hazards, its use in these applications has been limited.

Safety Precautions

DNPH is considered to be a hazardous substance and should be handled with care. It is toxic if ingested, inhaled, or absorbed through the skin. It can cause irritation to the skin, eyes, and respiratory system. Proper protective equipment, including gloves, goggles, and a respirator, should be worn when handling DNPH.

Conclusion

CAS 2516-47-4, or 2,4-dinitrophenylhydrazine (DNPH), is a highly reactive compound commonly used in the detection and quantification of carbonyl compounds in organic chemistry. It is also used in the synthesis of pyridine derivatives. While it has potential applications in other fields, its toxicity and potential health hazards have limited its use. Proper safety precautions should be taken when handling DNPH.