VAL-083, CAS 23261-20-3

VAL-083, CAS 23261-20-3, Stock 900g, Assay 98.68%, White powder, Water 0.24%, Single Impurity 0.38%.

VAL-083

VAL-083 is a bi-functional alkylating agent, with potential antineoplastic activity. Upon administration, VAL-083 crosses the blood brain barrier (BBB) and appears to be selective for tumor cells. This agent alkylates and crosslinks DNA which ultimately leads to a reduction in cancer cell proliferation. In addition, VAL-083 does not show cross-resistance to other conventional chemotherapeutic agents and has a long half-life in the brain.

Product Details:

Name: VAL-083

CAS#: 23261-20-3

Chemical Formula: C6H10O4

Exact Mass: 146.05791

Molecular Weight: 146.14

Elemental Analysis: C, 49.31; H, 6.90; O, 43.79

Specification:

Synonym: VAL083; VAL083; VAL083; Dianhydrodulcitol; Dianhydrogalactitol; Dulcitol Diepoxide;

IUPAC/Chemical Name: (1R,2S)-1-((R)-oxiran-2-yl)-2-((S)-oxiran-2-yl)ethane-1,2-diol

InChi Key: AAFJXZWCNVJTMK-GUCUJZIJSA-N

InChi Code: InChI=1S/C6H10O4/c7-5(3-1-9-3)6(8)4-2-10-4/h3-8H,1-2H2/t3-,4+,5+,6-

SMILES Code: O[C@@H]([C@@H]1OC1)[C@@H]([C@H]2OC2)O

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: