Imisopasem manganese(M40403), CAS 218791-21-0

  • Imisopasem manganese(M40403), CAS 218791-21-0

Imisopasem manganese(M40403), CAS 218791-21-0
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 218791-21-0
  • Stock: 890g
  • Assay: 98.64%

Imisopasem manganese(M40403), CAS 218791-21-0

Imisopasem manganese(M40403), CAS 218791-21-0Stock 890g, Assay 98.64%, White powderWater 0.24%, Single Impurity 0.32%.


Imisopasem manganese , also known as M40403, or GC4419, is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities. Upon administration, imisopasem manganese mimics the activity of MnSOD and scavenges reactive oxygen species (ROS), such as superoxide anion, which prevents oxygen free radical damage to macromolecules such as DNA. This reduces ROS-mediated lipid peroxidation, prevents apoptosis and protects against oxygen free radical-induced toxicity in normal tissues.

Product Details:

Name: Imisopasem manganese

CAS#: 218791-21-0

Chemical Formula: C21H35Cl2MnN5

Exact Mass:

Molecular Weight: 483.38

Elemental Analysis: C, 52.18; H, 7.30; Cl, 14.67; Mn, 11.37; N, 14.49


Synonym: M40403; M 40403; M-40403; CG4419; CG 4419; CG-4419; SC72325; SC-72325; SC 72325; Imisopasem manganese

IUPAC/Chemical Name: Manganese, dichloro[(4aR,13aR,17aR,21aR)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-11,7-nitrilo-7Hdibenzo[b,h][1,4,7,10]tetraazacycloheptadecine-κN5,κN13,κN18,κN21,κN22]-, (PB-7-11-2344'3')-.


InChi Code: InChI=1S/C21H35N5.2ClH.Mn/c1-3-10-20-18(8-1)22-12-13-23-19-9-2-4-11-21(19)25-15-17-7-5-6-16(26-17)14-24-20;;;/h5-7,18-25H,1-4,8-15H2;2*1H;/q;;;+2/p-2/t18-,19-,20-,21+;;;/m1.../s1

SMILES Code: [H][N@]1([C@H]2[C@H]3CCCC2)CC4=[N]5C(C[N]6([H])[C@H]7CCCC[C@H]7[N@@]([Mn]861(Cl)5Cl)([H])CC[N@@]38[H])=CC=C4

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001