CAS 1971920-73-6: Tolebrutinib

  • CAS 1971920-73-6: Tolebrutinib

CAS 1971920-73-6: Tolebrutinib
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  • CAS Number: 1971920-73-6
  • Stock: 197g
  • Assay: 99.13%

Tolebrutinib: CAS 1971920-73-6

Tolebrutinib: CAS 1971920-73-6Stock 197g, Assay 99.13%, White powderEOS is one of TOP GMP manufacturer


Tolebrutinib

Tolebrutinib is a selective and irreversible inhibitor of Bruton's tyrosine kinase (BTK) that has shown promise as a treatment for various B-cell malignancies. Clinical trials have demonstrated its efficacy in reducing disease progression and improving patient outcomes. Tolebrutinib may also have potential in the treatment of autoimmune disorders due to its ability to modulate immune cell activation and migration.


Product Details:

Name: Tolebrutinib
CAS#: 1971920-73-6
Chemical Formula: C26H25N5O3
Exact Mass: 455.1957
Molecular Weight: 455.518
Elemental Analysis: C, 68.56; H, 5.53; N, 15.37; O, 10.54


Specification:

Synonym: Tolebrutinib; SAR442168; SAR-442168; SAR 442168;
IUPAC/Chemical Name: 4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-(prop-2-enoyl)piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one
InChi Key: KOEUOFPEZFUWRF-LJQANCHMSA-N
InChi Code: InChI=1S/C26H25N5O3/c1-2-23(32)29-16-6-7-19(17-29)30-22-14-15-28-25(27)24(22)31(26(30)33)18-10-12-21(13-11-18)34-20-8-4-3-5-9-20/h2-5,8-15,19H,1,6-7,16-17H2,(H2,27,28)/t19-/m1/s1
SMILES Code: O=C(N1[C@H]2CN(C(C=C)=O)CCC2)N(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C1C=CN=C5N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
HS Tariff Code: 2934.99.9001


Certification:

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