Mobocertinib, CAS 1847461-43-1

  • Mobocertinib, CAS 1847461-43-1

Mobocertinib, CAS 1847461-43-1
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1847461-43-1
  • Stock: 1.22kg
  • Assay: 98.57%

Mobocertinib, CAS 1847461-43-1

Mobocertinib, CAS 1847461-43-1Stock 1218g, Assay 98.57%, White powderWater 0.21%, Single Impurity 0.68%.


Mobocertinib

Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs.


Product Details:

Name: Mobocertinib free base

CAS#: 1847461-43-1 (free base)

Chemical Formula: C32H39N7O4

Exact Mass: 585.3064

Molecular Weight: 585.71

Elemental Analysis: C, 65.62; H, 6.71; N, 16.74; O, 10.93


Specification:

Synonym: Mobocertinib; TAK-788; TAK 788; TAK788; AP32788; AP-32788; AP 32788;Mobocertinib free base

IUPAC/Chemical Name: propan-2-yl 2-[4-{[2-(dimethylamino)ethyl](methyl)amino}-2-methoxy-5-(prop-2-enamido)anilino]-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate

InChi Key: AZSRSNUQCUDCGG-UHFFFAOYSA-N

InChi Code: InChI=1S/C32H39N7O4/c1-9-29(40)34-24-16-25(28(42-8)17-27(24)38(6)15-14-37(4)5)35-32-33-18-22(31(41)43-20(2)3)30(36-32)23-19-39(7)26-13-11-10-12-21(23)26/h9-13,16-20H,1,14-15H2,2-8H3,(H,34,40)(H,33,35,36)

SMILES Code: O=C(C1=CN=C(NC2=CC(NC(C=C)=O)=C(N(CCN(C)C)C)C=C2OC)N=C1C3=CN(C)C4=C3C=CC=C4)OC(C)C

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: