CAS 1792180-81-4 : Ritlecitinib
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- CAS Number: 1792180-81-4
- Stock: 231g
- Assay: 99.39%
Ritlecitinib, CAS 1792180-81-4
Ritlecitinib, CAS 1792180-81-4, Stock 900g, Assay 99.39%, White to off-white powder, EOS is one of TOP GMP manufacturer
Ritlecitinib
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.
Product Details:
Name: PF-06651600 free base
CAS#: 1792180-81-4 (free base)
Chemical Formula: C15H19N5O
Exact Mass: 285.159
Molecular Weight: 285.35
Elemental Analysis: C, 63.14; H, 6.71; N, 24.54; O, 5.61
Specification:
Related CAS #: 1792180-81-4 (free base) 2140301-97-7 (malonate) 2192215-81-7 (tosylate) 2489392-29-0 (maleate)
Synonym: Ritlecitinib; PF-06651600; PF 06651600; PF06651600; PF-6651600; PF 6651600; PF6651600;
IUPAC/Chemical Name: 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one
InChi Key: CBRJPFGIXUFMTM-WDEREUQCSA-N
InChi Code: InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
SMILES Code: C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O
Appearance: white powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Certification: