Venglusta, CAS 1629063-78-0

  • Venglusta, CAS 1629063-78-0

Venglusta, CAS 1629063-78-0
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1629063-78-0
  • Stock: 671g
  • Assay: 98.64%

Venglusta, CAS 1629063-78-0

Venglusta, CAS 1629063-78-0Stock 671g, Assay 98.64%, White powderWater 0.21%, Single Impurity 0.42%.


Venglustat, also known as Ibiglustat, GZ402671, GZ-452; Genz-682452 and SAR402671, is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthesis of GL-3. Ibiglustat is potentially useful for treating Fabry disease. Fabry disease is a rare lysosomal storage disorder, which results in abnormal tissue deposits of a particular fatty substance called globotriaosylceramide (GL-3 or Gb3) throughout the body.

Product Details:

Name: Venglustat malate

CAS#: 1629063-78-0 (malate)

Chemical Formula: C24H30FN3O7S

Exact Mass:

Molecular Weight: 523.5764

Elemental Analysis: C, 55.06; H, 5.78; F, 3.63; N, 8.03; O, 21.39; S, 6.12


Related CAS #: 1401090-53-6 (free base)   1629063-79-1 (HCl)   1629063-80-4 (succinic acid)   1629063-78-0 (malate)  

Synonym: GZ/SAR402671A; Ibiglustat L-malate; Genz-682452-AU; SAR402671A; GZ-402671; GZ402671; GZ 402671; SAR402671; SAR-402671; SAR 402671; Genz-682452-AA; Ibiglustat; GZ-452; Genz-682452

IUPAC/Chemical Name: (3S)-1-azabicyclo[2.2.2]octan-3-yl N-{2-[2-(4-fluorophenyl)- 1,3-thiazol-4-yl]propan-2-yl}carbamate malate


InChi Code: InChI=1S/C20H24FN3O2S.C4H6O5/c1-20(2,17-12-27-18(22-17)14-3-5-15(21)6-4-14)23-19(25)26-16-11-24-9-7-13(16)8-10-24;5-2(4(8)9)1-3(6)7/h3-6,12-13,16H,7-11H2,1-2H3,(H,23,25);2,5H,1H2,(H,6,7)(H,8,9)/t16-;/m1./s1


Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001