CAS 160807-49-8: Indirubin-3’-oxime
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Indirubin-3’-oxime, CAS 160807-49-8:

Indirubin-3’-oxime, CAS 160807-49-8, Stock 123g, Assay 98.46%, White powder, Water 0.22%, Single Impurity 0.14%.

Indirubin-3’-oxime

Indirubin-3’-oxime is a potent inhibitor of glycogen synthase kinase 3β (GSK3β; IC50 = 22 nM).1 As GSK3β phosphorylates tau protein, indirubin-3’-oxime prevents tau phosphorylation both in vitro and in vivo at Alzheimer’s disease-relevant sites.

Product Details:

Name: Indirubin-3’-oxime

CAS#: 160807-49-8

Chemical Formula: C16H11N3O2

Exact Mass: 277.0851

Molecular Weight: 277.283

Elemental Analysis: C, 69.31; H, 4.00; N, 15.15; O, 11.54

Specification:

Synonym: Indirubin-3’-oxime

IUPAC/Chemical Name: 3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one

InChi Key: HBDSHCUSXQATPO-BRNLPKLHSA-N

InChi Code: InChI=1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17,21H,(H,18,20)/b15-13-,19-14-

SMILES Code: O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C/3=N/O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: