Rilzabrutinib (Prn-1008), CAS 1575596-29-0

  • Rilzabrutinib (Prn-1008), CAS 1575596-29-0

Rilzabrutinib (Prn-1008), CAS 1575596-29-0
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1575596-29-0
  • Stock: 1.77kg
  • Assay: 98.67%

Rilzabrutinib (Prn-1008), CAS 1575596-29-0

Rilzabrutinib (Prn-1008), CAS 1575596-29-0Stock 1769g, Assay 98.67%, White powderWater 0.89%, Single Impurity 0.57%.


Rilzabrutinib (Prn-1008), CAS 1575596-29-0

Rilzabrutinib, also known as PRN1008, is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK).


Product Details:

Name: Rilzabrutinib

CAS#: 1575596-29-0

Chemical Formula: C36H40FN9O3

Exact Mass: 665.3238

Molecular Weight: 665.7744

Elemental Analysis: C, 64.95; H, 6.06; F, 2.85; N, 18.93; O, 7.21


Specification:

Synonym: PRN1008; PRN 1008; PRN-1008; Rilzabrutinib;

IUPAC/Chemical Name: (R,E)-2-(3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4-methyl-4-(4-(oxetan-3-yl)piperazin-1-yl)pent-2-enenitrile

InChi Key: LCFFREMLXLZNHE-GBOLQPHISA-N

InChi Code: InChI=1S/C36H40FN9O3/c1-36(2,45-15-13-43(14-16-45)26-21-48-22-26)18-24(19-38)35(47)44-12-6-7-25(20-44)46-34-31(33(39)40-23-41-34)32(42-46)29-11-10-28(17-30(29)37)49-27-8-4-3-5-9-27/h3-5,8-11,17-18,23,25-26H,6-7,12-16,20-22H2,1-2H3,(H2,39,40,41)/b24-18+/t25-/m1/s1

SMILES Code: NC1=C2C(C3=C(C=C(OC4=CC=CC=C4)C=C3)F)=NN([C@H]5CN(CCC5)C(/C(C#N)=C/C(C)(N6CCN(C7COC7)CC6)C)=O)C2=NC=N1

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: