CAS 157212-55-0 : Bosentan

CAS 157212-55-0 : Bosentan
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 157212-55-0
  • Stock: 87g
  • Assay: 98.28%

Bosentan, CAS 157212-55-0:

Bosentan, CAS 157212-55-0Stock 87g, Assay 98.28%, White powderWater 0.19%, Single Impurity 0.3%.



Bosentan

Bosentan is a mixed Endothelin Receptor Antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR. It is used for the treatment of pulmonary artery hypertension (PAH). Bosentan blocks the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.


Product Details:

Name: Bosentan

CAS#: 157212-55-0 (Bosentan hydrate) 

Chemical Formula: C27H29N5O6S

Exact Mass: 551.18385

Molecular Weight: 551.61

Elemental Analysis: C, 58.79; H, 5.30; N, 12.70; O, 17.40; S, 5.81



Specification:

Related CAS #: 147536-97-8 (Bosentan free)   157212-55-0 (Bosentan hydrate)    

Synonym: Bosentan; bosentan anhydrous; bosentan monohydrate; Ro 47-0203; Ro-47-0203; Tracleer; Ro-47-0203.

IUPAC/Chemical Name: 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide

InChi Key: GJPICJJJRGTNOD-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)

SMILES Code: CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001



Certification: