CAS 157212-55-0 : Bosentan
(World's Largest Pharmaceutical Supplier)
- CAS Number: 157212-55-0
- Stock: 87g
- Assay: 98.28%
Bosentan, CAS 157212-55-0:
Bosentan, CAS 157212-55-0, Stock 87g, Assay 98.28%, White powder, Water 0.19%, Single Impurity 0.3%.
Bosentan
Bosentan is a mixed Endothelin Receptor Antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR. It is used for the treatment of pulmonary artery hypertension (PAH). Bosentan blocks the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Product Details:
Name: Bosentan
CAS#: 157212-55-0 (Bosentan hydrate)
Chemical Formula: C27H29N5O6S
Exact Mass: 551.18385
Molecular Weight: 551.61
Elemental Analysis: C, 58.79; H, 5.30; N, 12.70; O, 17.40; S, 5.81
Specification:
Related CAS #: 147536-97-8 (Bosentan free) 157212-55-0 (Bosentan hydrate)
Synonym: Bosentan; bosentan anhydrous; bosentan monohydrate; Ro 47-0203; Ro-47-0203; Tracleer; Ro-47-0203.
IUPAC/Chemical Name: 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
InChi Key: GJPICJJJRGTNOD-UHFFFAOYSA-N
InChi Code: InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)
SMILES Code: CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001