CAS 156722-18-8: Rostafuroxin
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Rostafuroxin, CAS 156722-18-8:

Rostafuroxin, CAS 156722-18-8, Stock 187g, Assay 98.22%, White powder, Water 0.17%, Single Impurity 0.23%.

Rostafuroxin

Rostafuroxin, also known as PST-2238, is an ouabain antagonist. Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain. Rostafuroxin ameliorates endothelial dysfunction and oxidative stress in resistance arteries from deoxycorticosterone acetate-salt hypertensive rats: the role of Na+K+-ATPase/ cSRC pathway. Rostafuroxin corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension.

Product Details:

Name: Rostafuroxin

CAS#: 156722-18-8

Chemical Formula: C23H34O4

Exact Mass: 374.2457

Molecular Weight: 374.52

Elemental Analysis: C, 73.76; H, 9.15; O, 17.09

Specification:

Synonym: PST-2238; PST 2238; PST2238; Rostafuroxin

IUPAC/Chemical Name: (3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethylhexadecahydro-14H-cyclopenta[a]phenanthrene-3,14,17-triol

InChi Key: AEAPORIZZWBIEX-DTBDINHYSA-N

InChi Code: InChI=1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1

SMILES Code: C[C@@]12[C@](C3=COC=C3)(O)CC[C@]1(O)[C@]4([H])CC[C@]5([H])C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: