CAS 155558-32-0 : Hydroxyfasudil HCl
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- CAS Number: 155558-32-0
- Stock: 213g
- Assay: 98.28%
Hydroxyfasudil HCl, CAS 155558-32-0:
Hydroxyfasudil HCl, CAS 155558-32-0, Stock 213g, Assay 98.28%, White powder, Water 0.17%, Single Impurity 0.31%.
Hydroxyfasudil HCl, CAS 155558-32-0
Hydroxyfasudil, aslo known as HA1100, is a cell-permeable hydroxylated metabolite of HA-1077, is a potent inhibitor of Rho-associated kinase (ROCK) (Ki = 150 nM). Hydroxyfasudil alleviates demyelination through the inhibition of MOG antibody and microglia activation in cuprizone mouse model.
Name: Hydroxyfasudil HCl
Chemical Formula: C14H18ClN3O3S
Molecular Weight: 343.826
Elemental Analysis: C, 48.91; H, 5.28; Cl, 10.31; N, 12.22; O, 13.96; S, 9.32
Related CAS #: 155558-32-0 (HCl) 105628-72-6 (free base)
Synonym: Hydroxyfasudil HCl, HA-1100 HCl; HA1100; HA 1100; Hydroxyfasudil hydrochlorid
IUPAC/Chemical Name: 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride
InChi Key: XWWFOUVDVJGNNG-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H
SMILES Code: O=S(N1CCNCCC1)(C2=CC=CC3=C2C=CN=C3O)=O.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001