Pemigatinib, CAS 1513857-77-6

  • Pemigatinib, CAS 1513857-77-6

Pemigatinib, CAS 1513857-77-6
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1513857-77-6
  • Stock: 955g
  • Assay: 98.61%

Pemigatinib, CAS 1513857-77-6

Pemigatinib, CAS 1513857-77-6Stock 955g, Assay 98.61%, White powderWater 0.24%, Single Impurity 0.32%.


Pemigatinib, also known as INCB054828, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) types 1, 2, and 3 (FGFR1/2/3), with potential antineoplastic activity. FGFR inhibitor INCB054828 binds to and inhibits FGFR1/2/3, which may result in the inhibition of FGFR1/2/3-related signal transduction pathways. This inhibits proliferation in FGFR1/2/3-overexpressing tumor cells.

Product Details:

Name: Pemigatinib

CAS#: 1513857-77-6 (free base)

Chemical Formula: C24H27F2N5O4

Exact Mass: 487.2031

Molecular Weight: 487.5

Elemental Analysis: C, 59.13; H, 5.58; F, 7.79; N, 14.37; O, 13.13


Related CAS #: 1513857-77-6 (free base)   1513857-77-6 (HCl)    

Synonym: Pemigatinib; INCB054828; INCB-054828; INCB 054828; INCB54828; INCB 54828; INCB-54828

IUPAC/Chemical Name: 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-[(morpholin-4-yl)methyl]-1,3,4,7-tetrahydro-2Hpyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one


InChi Code: InChI=1S/C24H27F2N5O4/c1-4-30-21-14(11-27-23-16(21)9-15(28-23)13-29-5-7-35-8-6-29)12-31(24(30)32)22-19(25)17(33-2)10-18(34-3)20(22)26/h9-11H,4-8,12-13H2,1-3H3,(H,27,28)


Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001