VU0467154, CAS 1451993-15-9

  • VU0467154, CAS 1451993-15-9

VU0467154, CAS 1451993-15-9
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  • CAS Number: 1451993-15-9
  • Stock: 891g
  • Assay: 98.66%

VU0467154, CAS 1451993-15-9

VU0467154, CAS 1451993-15-9Stock 891g, Assay 98.66%, White powderWater 0.24%, Single Impurity 0.32%.


VU0467154 is a potent and selective M4 PAM. VU0467154 exhibits robust APD-like and cognitive enhancing activity in rodents. Selective M4 PAMs could provide a therapeutic strategy for the treatment of HD.

Product Details:

Name: VU0467154

CAS#: 1451993-15-9

Chemical Formula: C17H15F3N4O3S2

Exact Mass: 444.0538

Molecular Weight: 444.4472

Elemental Analysis: C, 45.94; H, 3.40; F, 12.82; N, 12.61; O, 10.80; S, 14.43


Synonym: VU0467154, VU-0467154, VU 0467154

IUPAC/Chemical Name: 5-Amino-3,4-dimethyl-N-[[4-[(trifluoromethyl)sulfonyl]phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide


InChi Code: InChI=1S/C17H15F3N4O3S2/c1-8-9(2)23-24-16-12(8)13(21)14(28-16)15(25)22-7-10-3-5-11(6-4-10)29(26,27)17(18,19)20/h3-6H,7,21H2,1-2H3,(H,22,25)

SMILES Code: O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001