DCC-2618, CAS 1442472-39-0

  • DCC-2618, CAS 1442472-39-0

DCC-2618, CAS 1442472-39-0
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1442472-39-0
  • Stock: 830g
  • Assay: 98.56%

DCC-2618, CAS 1442472-39-0

DCC-2618, CAS 1442472-39-0, Stock 830g, Assay 98.56%, White powder, Water 0.22%, Single Impurity 0.24%.


Ripretinib, also known as DCC-2618, is a potent, orally active and selective KIT/PDGFR inhibitor with potential antineoplastic activity. DCC-2618 targets and binds to both wild-type and mutant forms of KIT and PDGFRa specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. In May 2020, FDA Approves Qinlock (ripretinib) for the Treatment of Fourth-Line Gastrointestinal Stromal Tumor

Product Details:

Name: Ripretinib free base

CAS#: 1442472-39-0 (free base)

Chemical Formula: C24H21BrFN5O2

Exact Mass: 509.0863

Molecular Weight: 510.37

Elemental Analysis: C, 56.48; H, 4.15; Br, 15.66; F, 3.72; N, 13.72; O, 6.27


Related CAS #: 1442472-39-0 (free base)   Ripretinib HCl   1225278-16-9 (wrong structure for DCC-2618)    

Synonym: DCC-2618; DCC 2618; DCC2618; DP 2618; DP-2618; DP2618; Ripretinib;

IUPAC/Chemical Name: 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea


InChi Code: InChI=1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,29,30,33)


Appearance: White to off-white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001