Selinexor, CAS 1393477-72-9

  • Selinexor, CAS 1393477-72-9

Selinexor, CAS 1393477-72-9
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1393477-72-9
  • Stock: 791g
  • Assay: 98.74%

Selinexor, CAS 1393477-72-9

Sln  Selinexor, CAS 1393477-72-9Stock 791g, Assay 98.74%, White powderWater 0.27%, Single Impurity 0.32%.


Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO1/CRM1 Inhibitor. Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia. Selinexor potentiates the antitumor activity of gemcitabine in human pancreatic cancer through inhibition of tumor growth, depletion of the antiapoptotic proteins, and induction of apoptosis. Selinexor has strong activity against primary AML cells while sparing normal stem and progenitor cells.

Product Details:

Name: Selinexor free base

CAS#: 1393477-72-9 (free base)

Chemical Formula: C17H11F6N7O

Exact Mass: 443.09293

Molecular Weight: 443.31

Elemental Analysis: C, 46.06; H, 2.50; F, 25.71; N, 22.12; O, 3.61


Related CAS #: 1393477-72-9 (free base)   1421923-86-5 (E-isomer)   1621865-82-4 (E-isomer)   Unknown (HCl)    

Synonym: KPT-330; KPT330; KPT 330; Selinexor; Xpovio

IUPAC/Chemical Name: (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide


InChi Code: InChI=1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1-

SMILES Code: O=C(NNC1=NC=CN=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001