TRILACICLIB, CAS 1374743-00-6

  • TRILACICLIB, CAS 1374743-00-6

TRILACICLIB, CAS 1374743-00-6
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1374743-00-6
  • Stock: 841g
  • Assay: 98.66%

TRILACICLIB, CAS 1374743-00-6

TRILACICLIB, CAS 1374743-00-6Stock 841g, Assay 98.66%, White powderWater 0.24%, Single Impurity 0.32%.


Trilaciclib

Trilaciclib is a potential first-in-class short-acting CDK4/6 inhibitor in development to preserve hematopoietic stem cells and enhance immune system function during chemotherapy. Trilaciclib may help protect bone marrow cells from damage caused by chemotherapy by inhibiting cyclin-dependent kinase 4/6, a type of enzyme. Trilaciclib is the first therapy in its class and was approved for medical use in the United States in February 2021.


Product Details:

Name: Trilaciclib

CAS#: 1374743-00-6 (free base)

Chemical Formula: C24H30N8O

Exact Mass: 446.2543

Molecular Weight: 446.559

Elemental Analysis: C, 64.55; H, 6.77; N, 25.09; O, 3.58



Specification:

Related CAS #: 1374743-00-6 (free base)   1977495-97-8 (HCl)    

Synonym: G1T28; G1T-28; G1T 28; Trilaciclib.

IUPAC/Chemical Name: 2'-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one

InChi Key: PDGKHKMBHVFCMG-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H30N8O/c1-30-9-11-31(12-10-30)18-5-6-20(25-15-18)28-23-26-14-17-13-19-22(33)27-16-24(7-3-2-4-8-24)32(19)21(17)29-23/h5-6,13-15H,2-4,7-12,16H2,1H3,(H,27,33)(H,25,26,28,29)

SMILES Code: O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C)CC6)C=C5)N=C43)CCCCC2

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certification: