CAS 1308672-74-3: Sulfatinib

  • CAS 1308672-74-3: Sulfatinib

CAS 1308672-74-3: Sulfatinib
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1308672-74-3
  • Stock: 310g
  • Assay: 99.50%

Sulfatinib, CAS 1308672-74-3

Sulfatinib, CAS 1308672-74-3, Stock 310g, Assay 99.5%, White powder, Water 0.27%, Single Impurity 0.5%.


Sulfatinib, also known as surufatinib, is an orally bioavailable, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3, and the fibroblast growth factor receptor type 1 (FGFR1), with potential antineoplastic and anti-angiogenic activities. Upon oral administration, sulfatinib binds to and inhibits VEGFRs and FGFR1 thereby inhibiting VEGFR- and FGFR1-mediated signal transduction pathways. This leads to a reduction of angiogenesis and tumor cell proliferation in VEGFR/FGFR1-overexpressing tumor cells. Expression of VEGFRs and FGFR1 may be upregulated in a variety of tumor cell types.

Product Details:

Name: Sulfatinib

CAS#: 1308672-74-3

Chemical Formula: C24H28N6O3S

Exact Mass: 480.1944

Molecular Weight: 480.587

Elemental Analysis: C, 59.98; H, 5.87; N, 17.49; O, 9.99; S, 6.67


Synonym: HMPL012; HMPL012; HMPL 012; Sulfatinib; surufatinib;

IUPAC/Chemical Name: N-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1H-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide


InChi Code: InChI=1S/C24H28N6O3S/c1-17-13-19-15-21(7-8-22(19)27-17)33-23-9-10-25-24(29-23)28-20-6-4-5-18(14-20)16-34(31,32)26-11-12-30(2)3/h4-10,13-15,26-27H,11-12,16H2,1-3H3,(H,25,28,29)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

HS Tariff Code: 2934.99.9001