Mitapivat, CAS 1260075-17-9 

Mitapivat, CAS 1260075-17-9 , Stock 480g, Assay 99.5%, White powder, Water 0.54%, Single Impurity 0.5%.

Mitapivat

Mitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.

Product Details:

Name: Mitapivat

CAS#: 1260075-17-9 (free)

Chemical Formula: C24H26N4O3S

Exact Mass: 450.1726

Molecular Weight: 450.557

Elemental Analysis: C, 63.98; H, 5.82; N, 12.44; O, 10.65; S, 7.12

Specification:

Synonym: AG348; AG-348; AG 348; PKR-IN-1; PKM2 activator 1020; PKM2 activator; Mitapivat.

IUPAC/Chemical Name: N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide

InChi Key: XAYGBKHKBBXDAK-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2

SMILES Code: O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

HS Tariff Code: 2934.99.9001

Certification: