Tenapanor, CAS 1234423-95-0

  • Tenapanor, CAS 1234423-95-0

Tenapanor, CAS 1234423-95-0
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1234423-95-0
  • Stock: 810g
  • Assay: 98.62%

Tenapanor, CAS 1234423-95-0

Tenapanor, CAS 1234423-95-0Stock 810g, Assay 98.62%, White powderWater 0.24%, Single Impurity 0.32%.


Tenapanor

Tenapanor, also known as AZD-1722 and RDX 5791, is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Tenapanor is currently in clinical trials.


Product Details:

Name: Tenapanor free base

CAS#: 1234423-95-0 (free base)

Chemical Formula: C50H66Cl4N8O10S2

Exact Mass: 1142.3097

Molecular Weight: 1145.044

Elemental Analysis: C, 52.45; H, 5.81; Cl, 12.38; N, 9.79; O, 13.97; S, 5.60



Specification:

Related CAS #: 1234423-95-0 (free base)   1234365-97-9 (2HCl)  

Synonym: AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor free base; Ibsrela.

IUPAC/Chemical Name: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide

InChi Key: DNHPDWGIXIMXSA-CXNSMIOJSA-N

InChi Code: InChI=1S/C50H66Cl4N8O10S2/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)58-14-18-70-22-24-72-20-16-60-74(67,68)40-10-6-8-36(26-40)44-32-62(2)34-46-42(44)28-38(52)30-48(46)54/h5-10,25-30,43-44,59-60H,3-4,11-24,31-34H2,1-2H3,(H2,55,57,63)(H2,56,58,64)/t43-,44-/m0/s1

SMILES Code: O=S(C1=CC=CC([C@@H]2CN(C)CC3=C2C=C(Cl)C=C3Cl)=C1)(NCCOCCOCCNC(NCCCCNC(NCCOCCOCCNS(=O)(C4=CC=CC([C@@H]5CN(C)CC6=C5C=C(Cl)C=C6Cl)=C4)=O)=O)=O)=O

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001



Certification: