Tenapanor HCl, CAS 1234365-97-9

  • Tenapanor HCl, CAS 1234365-97-9

Tenapanor HCl, CAS 1234365-97-9
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  • CAS Number: 1234365-97-9
  • Stock: 871g
  • Assay: 98.69%

Tenapanor HCl, CAS 1234365-97-9

Tenapanor HCl, CAS 1234365-97-9Stock 871g, Assay 98.69%, White powderWater 0.24%, Single Impurity 0.32%.

Tenapanor HCl

Tenapanor, also known as AZD-1722 and RDX 5791, is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects.

Product Details:

Name: Tenapanor HCl

CAS#: 1234365-97-9 (2HCl)

Chemical Formula: C50H68Cl6N8O10S2

Exact Mass: 1144.3254

Molecular Weight: 1217.96

Elemental Analysis: C, 49.31; H, 5.63; Cl, 17.46; N, 9.20; O, 13.14; S, 5.26


Related CAS #: 1234423-95-0 (free base)   1234365-97-9 (2HCl)    

Synonym: AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor; Tenapanor hydrochloride; Tenapanor dihydrochloride; Ibsrela.

IUPAC/Chemical Name: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide dihydrochloride


InChi Code: InChI=1S/C50H66Cl4N8O10S2.2ClH/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)58-14-18-70-22-24-72-20-16-60-74(67,68)40-10-6-8-36(26-40)44-32-62(2)34-46-42(44)28-38(52)30-48(46)54;;/h5-10,25-30,43-44,59-60H,3-4,11-24,31-34H2,1-2H3,(H2,55,57,63)(H2,56,58,64);2*1H/t43-,44-;;/m0../s1


Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO and water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001