Vibegron, CAS 1190389-15-1

  • Vibegron, CAS 1190389-15-1

Vibegron, CAS 1190389-15-1
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1190389-15-1
  • Stock: 839g
  • Assay: 98.67%

Vibegron, CAS 1190389-15-1

Vibegron, CAS 1190389-15-1Stock 839g, Assay 98.67%, White powderWater 0.34%, Single Impurity 0.42%.


Vibegron, also known as MK-4618, is a potent and selective Beta 3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder (OAB). Vibegron has no unacceptable toxicity in preclinical species. Vibegron is currently in Phase 3 human clinical trials for the treatment of OAB. β3-adrenergic receptor (β3-AR) agonists were investigated as potential treatments for obesity and/or diabetes owing to their ability to induce lipolysis, thermogenesis, and antihyperglycemic activity in preclinical species.

Product Details:

Name: Vibegron

CAS#: 1190389-15-1

Chemical Formula: C26H28N4O3

Exact Mass: 444.2161

Molecular Weight: 444.535

Elemental Analysis: C, 70.25; H, 6.35; N, 12.60; O, 10.80


Synonym: MK-4618; MK 4618; MK4618; KRP114V; KRP-114V; KRP 114V; Vibegron; Gemtesa;

IUPAC/Chemical Name: (S)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxamide


InChi Code: InChI=1S/C26H28N4O3/c31-24-14-15-27-23-13-12-22(30(23)24)26(33)29-19-8-6-17(7-9-19)16-20-10-11-21(28-20)25(32)18-4-2-1-3-5-18/h1-9,14-15,20-22,25,28,32H,10-13,16H2,(H,29,33)/t20-,21+,22-,25+/m0/s1

SMILES Code: O=C([C@@H]1CCC2=NC=CC(N21)=O)NC3=CC=C(C[C@H]4N[C@@H]([C@H](O)C5=CC=CC=C5)CC4)C=C3

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001