Sitravatinib, CAS 1123837-84-2

  • Sitravatinib, CAS 1123837-84-2

Sitravatinib, CAS 1123837-84-2
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1123837-84-2
  • Stock: 1.33kg
  • Assay: 98.52%

Sitravatinib, CAS 1123837-84-2

Sitravatinib, CAS 1123837-84-2Stock 1328g, Assay 98.52%, White powderWater 0.19%, Single Impurity 0.28%.


Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. MGCD516 treatment resulted in significant blockade of phosphorylation of potential driver RTKs and induced potent anti-proliferative effects in vitro. MGCD516 treatment of tumor xenografts in vivo resulted in significant suppression of tumor growth.

Product Details:

Name: Sitravatinib

CAS#: 1123837-84-2

Chemical Formula: C33H29F2N5O4S

Exact Mass: 629.1908

Molecular Weight: 629.68

Elemental Analysis: C, 62.95; H, 4.64; F, 6.03; N, 11.12; O, 10.16; S, 5.09


Synonym: MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516; Sitravatinib; CAS#1123837-84-2.

IUPAC/Chemical Name: N-(3-fluoro-4-((2-(5-(((2-methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide


InChi Code: InChI=1S/C33H29F2N5O4S/c1-43-15-14-37-18-20-2-8-25(39-19-20)29-17-26-30(45-29)28(10-13-38-26)44-27-9-7-23(16-24(27)35)40(22-5-3-21(34)4-6-22)32(42)33(11-12-33)31(36)41/h2-10,13,16-17,19,37H,11-12,14-15,18H2,1H3,(H2,36,41)


Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001