Apabetalone, CAS 1044870-39-4

  • Apabetalone, CAS 1044870-39-4

Apabetalone, CAS 1044870-39-4
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1044870-39-4
  • Stock: 884g
  • Assay: 98.19%

Apabetalone, CAS 1044870-39-4

Apabetalone, CAS 1044870-39-4Stock 884g, Assay 98.19%, White powderWater 0.68%, Single Impurity 0.54%.


Apabetalone

Apabetalone, also known as RVX-208, is a potent inhibitor of BET bromodomains. RVX-208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX-208 increases the production of ApoA-I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL-C, but the molecular target was not previously reported. RVX-208 may be a promising new approach to the treatment of atherosclerosis.


Product Details:

Name: Apabetalone

CAS#: 1044870-39-4

Chemical Formula: C20H22N2O5

Exact Mass: 370.15287

Molecular Weight: 370.39908

Elemental Analysis: C, 64.85; H, 5.99; N, 7.56; O, 21.60


Specification:

Synonym: RVX208; RVX 208; RVX-208; Apabetalone.

IUPAC/Chemical Name: 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one

InChi Key: NETXMUIMUZJUTB-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H22N2O5/c1-11-7-13(8-12(2)18(11)27-6-5-23)19-21-15-9-14(25-3)10-16(26-4)17(15)20(24)22-19/h7-10,23H,5-6H2,1-4H3,(H,21,22,24)

SMILES Code: O=C1NC(C2=CC(C)=C(OCCO)C(C)=C2)=NC3=C1C(OC)=CC(OC)=C3

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: