JPH203, CAS 1037592-40-7

  • JPH203, CAS 1037592-40-7

JPH203, CAS 1037592-40-7
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1037592-40-7
  • Stock: 994g
  • Assay: 98.74%

JPH203, CAS 1037592-40-7

JPH203, CAS 1037592-40-7Stock 994g, Assay 98.74%, White powderWater 0.34%, Single Impurity 0.52%.


JPH203, also known as KYT-0353, is a potent and selective LAT1 selective ( L-type amino acid transporter 1) inhibitor. JPH203 can very potently inhibit l-leucine uptake. JPH203 inhibits YD-38 cell growth. JPH203 up-regulated the population of apoptotic YD-38 cells through the activation of apoptotic factors, including caspases and PARP.

Product Details:

Name: JPH203 free base

CAS#: 1037592-40-7 (free base)

Chemical Formula: C23H19Cl2N3O4

Exact Mass: 471.0753

Molecular Weight: 472.322

Elemental Analysis: C, 58.49; H, 4.05; Cl, 15.01; N, 8.90; O, 13.55


Related CAS #: 1597402-27-1 (2HCl)   1037592-40-7 (free base)   1597402-28-2 (complex with beta cyclodextrin)    

Synonym: JPH-203; JPH 203; KYT-0353; KYT 0353; KYT0353; nanvuranlat

IUPAC/Chemical Name: (S)-2-amino-3-(4-((5-amino-2-phenylbenzo[d]oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid


InChi Code: InChI=1S/C23H19Cl2N3O4/c24-16-6-12(8-18(27)23(29)30)7-17(25)21(16)31-11-14-9-15(26)10-19-20(14)32-22(28-19)13-4-2-1-3-5-13/h1-7,9-10,18H,8,11,26-27H2,(H,29,30)/t18-/m0/s1

SMILES Code: O=C(O)[C@@H](N)CC1=CC(Cl)=C(OCC2=C(OC(C3=CC=CC=C3)=N4)C4=CC(N)=C2)C(Cl)=C1

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Slightly soluble in DMSO (50mg/mL), not soluble in water. Soluble in 5% hydrochloride

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO with a few drops of 5%HCl

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001