Regorafenib monohydrate, CAS 1019206-88-2

Regorafenib monohydrate, CAS 1019206-88-2, Stock 350g, Assay 99.8%, White powder, Water 0.5%, Single Impurity 0.2%.

Regorafenib monohydrate

Regorafenib monohydrate is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1.

Product Details:

Name: Regorafenib monohydrate

CAS#: 1019206-88-2

Chemical Formula: C21H17ClF4N4O4

Exact Mass: 500.0874

Molecular Weight: 500.83

Elemental Analysis: C, 50.36; H, 3.42; Cl, 7.08; F, 15.17; N, 11.19; O, 12.78

Specification:

Synonym: Regorafenib monohydrate; BAY 73-4506 monohydrate; BAY 734506 monohydrate; BAY 73 4506 monohydrate

IUPAC/Chemical Name: 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide hydrate

InChi Key: ZOPOQLDXFHBOIH-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H15ClF4N4O3.H2O/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26;/h2-10H,1H3,(H,27,31)(H2,29,30,32);1H2

SMILES Code: O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F.O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: