CAS 1010100-07-8: CC-885
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CAS Number: 1010100-07-8
Stock: 428g
Assay: 99.50%

CC-885, CAS 1010100-07-8

CC-885, CAS 1010100-07-8, Stock 428g, Assay 99.5%, White powder, Water 0.27%, Single Impurity 0.5%.

CC-885

CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through the degradation of GSPT1. was demonstrated to mediate antitumor effects through the recruitment and degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 (also named eRF3a) is a translation termination factor that binds eukaryotic translation termination factor 1 (eFR1) to mediate stop codon recognition and nascent protein release from the ribosome.

Product Details:

Name: CC-885
CAS#: 1010100-07-8
Chemical Formula: C22H21ClN4O4
Exact Mass: 440.1251
Molecular Weight: 440.884
Elemental Analysis: C, 59.93; H, 4.80; Cl, 8.04; N, 12.71; O, 14.52

Specification:

Synonym: CC-885, CC 885, CC885.
IUPAC/Chemical Name: N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea
InChi Key: DOEVCIHTTTYVCC-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H21ClN4O4/c1-12-2-4-15(9-17(12)23)25-22(31)24-10-13-3-5-16-14(8-13)11-27(21(16)30)18-6-7-19(28)26-20(18)29/h2-5,8-9,18H,6-7,10-11H2,1H3,(H2,24,25,31)(H,26,28,29)
SMILES Code: O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4
Appearance: Off white to light purple solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001