CAS 1010100-07-8: CC-885

  • CAS 1010100-07-8: CC-885

CAS 1010100-07-8: CC-885
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1010100-07-8
  • Stock: 428g
  • Assay: 99.50%

CC-885, CAS 1010100-07-8

CC-885, CAS 1010100-07-8, Stock 428g, Assay 99.5%, White powder, Water 0.27%, Single Impurity 0.5%.


CC-885

CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through the degradation of GSPT1. was demonstrated to mediate antitumor effects through the recruitment and degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 (also named eRF3a) is a translation termination factor that binds eukaryotic translation termination factor 1 (eFR1) to mediate stop codon recognition and nascent protein release from the ribosome.



Product Details:

Name: CC-885

CAS#: 1010100-07-8

Chemical Formula: C22H21ClN4O4

Exact Mass: 440.1251

Molecular Weight: 440.884

Elemental Analysis: C, 59.93; H, 4.80; Cl, 8.04; N, 12.71; O, 14.52


Specification:

Synonym: CC-885, CC 885, CC885.

IUPAC/Chemical Name: N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea

InChi Key: DOEVCIHTTTYVCC-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H21ClN4O4/c1-12-2-4-15(9-17(12)23)25-22(31)24-10-13-3-5-16-14(8-13)11-27(21(16)30)18-6-7-19(28)26-20(18)29/h2-5,8-9,18H,6-7,10-11H2,1H3,(H2,24,25,31)(H,26,28,29)

SMILES Code: O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4

Appearance: Off white to light purple solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certification: