CX-4945, CAS 1009820-21-6
(World's Largest Pharmaceutical Supplier)

CX-4945, CAS 1009820-21-6

CX-4945, CAS 1009820-21-6, Stock 1532g, Assay 98.32%, White powder, Water 0.34%, Single Impurity 0.64%.

CX-4945

Silmitasertib, also know as CX-4945, is an orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. CK2 inhibitor CX-4945 selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumor growth and survival.

Product Details:

Name: CX4945 (Silmitasertib)

CAS#: 1009820-21-6 (free acid)

Chemical Formula: C19H12ClN3O2

Exact Mass: 349.0618

Molecular Weight: 349.77

Elemental Analysis: C, 65.24; H, 3.46; Cl, 10.14; N, 12.01; O, 9.15

Specification:

Synonym: CX4945 CX-4945; CX 4945; Silmitasertib.

IUPAC/Chemical Name: 5-((3-chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid

InChi Key: MUOKSQABCJCOPU-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)

SMILES Code: O=C(C1=CC=C2C(N=C(NC3=CC=CC(Cl)=C3)C4=C2C=NC=C4)=C1)O

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO (up to 15mg/mL)

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: