Avapritinib, 1703793-34-3, Stock 186g, World biggest supplier.

Avapritinib, 1703793-34-3, Stock186g, World biggest supplier. 

Avapritinib, 1703793-34-3, HPLC 99.26%, HNMR, MASS, HPLC, COA, MSDS we supply.
Avapritinib, 1703793-34-3, batch size 1kg, White powder. 

Avapritinib, also known as BlU-285, is a potent and selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease. BLU-285 is currently being developed by Blueprint.





Name: Avapritinib
CAS#: 1703793-34-3
Chemical Formula: C26H27FN10
Exact Mass: 498.2404
Molecular Weight: 498.5704
Elemental Analysis: C, 62.64; H, 5.46; F, 3.81; N, 28.09

Synonym: BLU-285; BLU 285; BLU285, Avapritinib
IUPAC/Chemical Name: (S)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine
InChi Key: DWYRIWUZIJHQKQ-SANMLTNESA-N
InChi Code: InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1
SMILES Code: CN1N=CC(C2=CN3C(C(N4CCN(C5=NC=C([C@@](C)(N)C6=CC=C(F)C=C6)C=N5)CC4)=NC=N3)=C2)=C1
Appearance: White to off-white solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001


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