Larotrectinib, 1223403-58-4, batch size 100kg.

EOS trial produce Larotrectinib 1223403-58-4 in 2018. Batch size 100g.


EOS pilot produce Larotrectinib 1223403-58-4 in 2020. Batch size 10-50kg.


EOS GMP & FDA produce Larotrectinib 1223403-58-4 in 2021. Batch size 100kg. Approved by some big customers. Larotrectinib assay more than 99.5%, HPLC, HNMR, LCMS is ok.


Larotrectinib, also known as ARRY-470 and LOXO-101, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC.






Larotrectinib 1223403-58-4 Intermediates all from GMP plant,


Larotrectinib Intermediates, 1218935-58-0, stock 55kg, Assay 99.7%, Single Impurity less than 0.1%.


Larotrectinib Intermediates, 1218935-59-1 , stock 75kg, Assay 99.5%, Single Impurity less than 0.2%.


Larotrectinib Intermediates, 1218935-60-4, stock 45kg, Assay 99.2%, Single Impurity less than 0.1%.


Larotrectinib Intermediates, 1223404-88-3, stock 50kg, Assay 99.7%, Single Impurity less than 0.2%.


Larotrectinib Intermediates, 1223404-89-4 , stock 56kg, Assay 99.1%, Single Impurity less than 0.1%.


Larotrectinib Intermediates, 1223404-90-7, stock 35kg, Assay 99.7%, Single Impurity less than 0.2%.


Larotrectinib Intermediates, 1363380-51-1, stock 85kg, Assay 99.3%, Single Impurity less than 0.1%.


Larotrectinib Intermediates, 1919868-77-1, stock 55kg, Assay 99.5%, Single Impurity less than 0.1%.


Larotrectinib Intermediates, 29274-22-4 , stock 150kg, Assay 99.1%, Single Impurity less than 0.1%.


Larotrectinib Intermediates, 29274-24-6 , stock 100kg, Assay 99.0%, Single Impurity less than 0.1%.


Larotrectinib Intermediates, 33884-43-4, stock 95kg, Assay 99.9%, Single Impurity less than 0.1%.


Larotrectinib FORM 1223403-58-4 (free base),1223405-08-0 (sulfate)  





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