Silvestrol, CAS 697235-38-4

  • Silvestrol, CAS 697235-38-4

Silvestrol, CAS 697235-38-4
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 697235-38-4
  • Stock: 100g
  • Assay: 98.50%

Silvestrol, CAS 697235-38-4

Silvestrol, CAS 697235-38-4, Stock 100g, Assay 98.5%, White powder, Water 0.03%, Single Impurity 0.04%.


Silvestrol

Silvestrol, a member of flavagline family of natural products from the genus of Aglaia exhibiting anti-cancer activity in vitro and in vivo. Silvestrol induces early autophagy and apoptosis in human melanoma cells. Silvestrol exhibits direct anti-tumor activity while preserving innate and adaptive immunity against EBV-driven lymphoproliferative disease. Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia.


Produt Details:

Name: Silvestrol
CAS#: 697235-38-4
Chemical Formula: C34H38O13
Exact Mass: 654.23
Molecular Weight: 654.665
Elemental Analysis: C, 62.38; H, 5.85; O, 31.77




Specification:

Synonym: Silvestrol

IUPAC/Chemical Name: methyl (1R,2R,3S,3aR,8bS)-6-[[(3R,6R)-6-[(1R)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate

InChi Key: GVKXFVCXBFGBCD-YKBYZOLHSA-N

InChi Code: InChI=1S/C34H38O13/c1-40-20-12-10-19(11-13-20)34-27(18-8-6-5-7-9-18)26(30(38)42-3)29(37)33(34,39)28-23(41-2)14-21(15-24(28)47-34)45-32-31(43-4)44-17-25(46-32)22(36)16-35/h5-15,22,25-27,29,31-32,35-37,39H,16-17H2,1-4H3/t22-,25-,26-,27-,29-,31-,32?,33+,34+/m1/s1

SMILES Code: O=C([C@H]([C@H]1C2=CC=CC=C2)[C@@H](O)[C@]3(O)[C@@]1(C4=CC=C(OC)C=C4)OC5=C3C(OC)=CC(OC6O[C@@H]([C@H](O)CO)CO[C@H]6OC)=C5)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certification: