Product Details:

Name: Filgotinib

CAS#: 1206161-97-8 (free base)

Chemical Formula: C21H23N5O3S

Exact Mass: 425.15216

Molecular Weight: 425.5

Elemental Analysis: C, 59.28; H, 5.45; N, 16.46; O, 11.28; S, 7.54

Specification:

Synonym: GLPG0634; GLPG 0634; GLPG-0634. Filgotinib; PubChemSID 163643231

IUPAC/Chemical Name: N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide.

InChi Key: RIJLVEAXPNLDTC-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27)

SMILES Code: O=C(C1CC1)NC2=NN3C(C4=CC=C(CN5CCS(CC5)(=O)=O)C=C4)=CC=CC3=N2.

Appearance: White to off-white-solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: GLPG0634 was formulated in polyethyleneglycol 200/0.9% NaCl (60/40; v/v) for i.v. administration and in 0.5% (v/v) methylcellulose for oral administration for all in vivo studies

HS Tariff Code: 2934.99.9001