Mitapivat, CAS 1260075-17-9, Stock 891g, Assay 98.64%, White powder, Water 0.24%, Single Impurity 0.32%.
Mitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.
Name: Mitapivat
CAS#: 1260075-17-9 (free)
Chemical Formula: C24H26N4O3S
Exact Mass: 450.1726
Molecular Weight: 450.557
Elemental Analysis: C, 63.98; H, 5.82; N, 12.44; O, 10.65; S, 7.12
Synonym: AG348; AG-348; AG 348; PKR-IN-1; PKM2 activator 1020; PKM2 activator; Mitapivat.
IUPAC/Chemical Name: N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide
InChi Key: XAYGBKHKBBXDAK-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2
SMILES Code: O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
