COA
No files available
NMR
No files available
Primary record
Silevertinib
- CAS
- 2607829-38-7
- Stock
- 5374g
- Purity
- 98.2%
- PubChem CID
- 156071569
- SMILES
- CN1C[C@H]2C[C@]2(C1)C#CC3=CC4=C(C=C3NC(=O)/C=C/CN5CCOCC5)C(=NC=N4)NC6=C(C(=CC=C6)Cl)F
- Molecular Formula
- C30H30ClFN6O2
- Molecular Weight
- 561.061
- Exact Mass
- 560.2103
- InChI
- InChI=1S/C30H30ClFN6O2/c1-37-17-21-16-30(21,18-37)8-7-20-14-26-22(29(34-19-33-26)36-24-5-2-4-23(31)28(24)32)15-25(20)35-27(39)6-3-9-38-10-12-40-13-11-38/h2-6,14-15,19,21H,9-13,16-18H2,1H3,(H,35,39)(H,33,34,36)/b6-3+/t21-,30+/m1/s1
- InChIKey
- LMOVDLRMIRLIJF-TUVXKDNKSA-N
- LogP
- 4.296
- TPSA
- 82.62
Names and synonyms
- Silevertinib
- EGFR-IN-76
- BDTX-1535
- silevertinib [INN]
- RP9F537KVY
- 2607829-38-7
- RefChem:1098520
- SILEVERTINIB [USAN]
- BDTX1535
- orb1982304
- SCHEMBL22983932
- SCHEMBL29719191
- BDTX 1535
- GTPL13371
- WLZ3775
- GLXC-27558
- EX-A7760
- AT43356
- DA-73041
- TS-09677
- Compound No. 37 [WO2021030711]
- HY-153268
- CS-0675480
- (E)-N-(4-((3-Chloro-2-fluorophenyl)amino)-7-(((1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-1-yl)ethynyl)quinazolin-6-yl)-4-morpholinobut-2-enamide
- A969997
- (E)-N-[4-(3-chloro-2-fluoroanilino)-7-[2-[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-1-yl]ethynyl]quinazolin-6-yl]-4-morpholin-4-ylbut-2-enamide
- (2E)-N-[4-[(3-Chloro-2-fluorophenyl)amino]-7-[2-[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hex-1-yl]ethynyl]-6-quinazolinyl]-4-(4-morpholinyl)-2-butenamide
- -2-Butenamide, N-[4-[(3-chloro-2-fluorophenyl)amino]-7-[2-[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hex-1-yl]ethynyl]-6-quinazolinyl]-4-(4-morpholinyl)-, (2E)-
- 2-Butenamide, N-[4-[(3-chloro-2-fluorophenyl)amino]-7-[2-[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hex-1-yl]ethynyl]-6-quinazolinyl]-4-(4-morpholinyl)-, (2E)-