Taletrectinib Uses
Taletrectinib (DS-6051b) is a potent, orally active, next-generation selective ROS1/NTRK inhibitor. Taletrectinib exhibits strong inhibitory activity against recombinant ROS1, NTRK1, and NTRK3 with IC50 values of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other anti-Crizotinib ROS1 mutants.
| Molecular formula | C29H34FN5O5 |
|---|---|
| molecular weight | 551.61 |
| InChIKey | DORJQZDOULKINH-QNBGGDODSA-N |
| SMILES | CC(N)COc1ccc(-c2cnc3ccc(NC(C)c4cccc(F)c4)nn23)cc1.O=C(O)CCCCC(=O)O |
| Storage conditions |
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EOS Med CDMO supplies Taletrectinib for research and development use.
We support scale-up production up to kilogram levels and provide full Drug Master File (DMF) documentation support.
Every shipment comes with complete technical dossiers, including COA, MSDS, and analytical data (HPLC/HNMR), to ensure seamless regulatory compliance for your project.
Compliance Notice: This product is supplied strictly for research and development (R&D) use only. It is not intended for human or veterinary diagnostic or therapeutic applications.
Supply Capability
CAS: 1505515-69-4
stock: 500 kg
Purity: >98% (HPLC)
Chemical name ：DS-6051b
Documentation (on request): COA / HNMR / MSDS / DMF
Specifications
Synonyms: AB-106, DS-6051b
Transportation Conditions: This product is a non-hazardous chemical and should be transported at room temperature. It can be stably stored for several weeks during normal transportation and customs clearance.
Storage Conditions: Short-term (days to weeks) storage at 0-4°C; long-term (months to years) storage at -20°C.
Shelf Life: Over 2 years under proper storage conditions.
HS Code: 2934.99.9001