How to synthesis Rotraxatehydrochloride

Oct 25, 2018

Original Route of Synthesis of  Rotraxatehydrochloride yield is about 10%, impurity is 2%, unknown impurity is 1%.


EOS Med Chem use the new Route of Synthesis of Rotraxatehydrochloride, yield improve 30%.


Reduced Rotraxatehydrochloride synthesis steps, Remove unknown impurity, Remove Toxic Chemicals, Impurity is less than 1%, Assay more than 99%, Water by KF less than 0.5%.


Below is EOS Med Chem Route of Synthesis of Rotraxatehydrochloride, each steps we have MSDS, COA, if you have interesting, pls contact me.

1.
English Name:3-[4-[4-(aminomethyl)cyclohexanecarbonyl]phenyl]propanoic acid,hydrochloride
Other Name:Rotraxate HCl;
Cumelon; Tei 5103; TG-51; Rotraxate hydrochloride;
CAS#:82085-94-7
分子式:C17H24ClNO3
分子量:325.83000
精确质量:325.14400 PSA:80.39000 LogP:4.15390

2.
Rotraxatehydrochloride, 82085-94-7;92071-51-7(free)  and intermediates:
Rotraxatehydrochloride, 82085-94-7; 92071-51-7(free) Intermediate  1197-18-8
Rotraxatehydrochloride, 82085-94-7;92071-51-7(free) Intermediate  27687-16-7
Rotraxatehydrochloride, 82085-94-7;92071-51-7(free) Intermediate  103-25-3
Rotraxatehydrochloride, 82085-94-7;92071-51-7(free) Intermediate  102196-03-2


 

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