Biggest LOXO-292 2222755-14-6 supplier

Feb 22, 2019
Biggest LOXO-292,  2222755-14-6 supplier, LOXO-292, world biggest supplier. 
LOXO-292, stock 210g, HPLC 99.8%, HNMR, COA, MSDS is ok.
This is only for R&D use, can not use in human, animal.

We have started researching the LOXO-292,  2222755-14-6 since 2018. We have already carried out batch production, also have completed the development of quality standards and process validation. The stable process is the guarantee of product quality. For these two products, we use HPLC-UV detection instead of other companies' HPLC-ELSD test, Our detection method is more sensitive.

LOXO-292 (ARRY-192) is an oral and selective investigational drug in clinical development for the treatment of patients with cancers that harbor abnormalities in the rearranged during transfection (RET) kinase.


​Name: LOXO-292 
CAS#: 2222755-14-6 
Chemical Formula: C29H31N9O3 
Exact Mass: 553.255 
Molecular Weight: 553.627 
Elemental Analysis: C, 62.92; H, 5.64; N, 22.77; O, 8.67
Synonym: LOXO-292; LOXO292; LOXO 292; ARRY-192; ARRY192; ARRY 192

IUPAC/Chemical Name: 4-(5-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyrazin-2-yl)-6-(((R)-morpholin-2-yl)methoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile

InChi Key: GTQISTQEBXXLPC-UBVWURDFSA-N

InChi Code: InChI=1S/C29H31N9O3/c1-39-28-3-2-19(9-34-28)14-37-21-6-22(37)16-36(15-21)27-13-32-26(12-33-27)25-7-23(41-18-24-11-31-4-5-40-24)17-38-29(25)20(8-30)10-35-38/h2-3,7,9-10,12-13,17,21-22,24,31H,4-6,11,14-16,18H2,1H3/t21?,22?,24-/m1/s1

SMILES Code: N#CC1=C2C(C3=NC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OC[C@H]7CNCCO7)=CN2N=C1
 
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