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CAS Number：1005402-19-6
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SMILES：CAS 1005402-19-6: IrdabisantIrdabisant, CAS?1005402-19-6,?Stock?259g,?Assay?99.7%,?White powder, Water?0.19%,?Single Impurity?0.3%.IrdabisantIrdabisant, also known as CEP-26401, is a potent, selective histamine H3 receptor inverse agonist. High affinity of CEP-26401 for H?R was demonstrated in radioligand binding displacement assays in rat brain membranes (K(i) = 2.7 ?? 0.3 nM) and recombinant rat and human H?R-expressing systems (K(i) = 7.2 ?? 0.4 and 2.0 ?? 1.0 nM, respectively). CEP-26401 displayed potent antagonist and inverse agonist activities in [??S]guanosine 5'-O-(??-thio)triphosphate binding assays. CEP-26401 may also have therapeutic utility in treating schizophrenia or as adjunctive therapy to approved antipsychotics.Product Details:Name: IrdabisantCAS#: 1005402-19-6 (free base)Chemical Formula: C18H23N3O2Exact Mass: 313.179Molecular Weight: 313.401Elemental Analysis: C, 68.98; H, 7.40; N, 13.41; O, 10.21Specification:Synonym: CEP-26401; CEP 26401; CEP26401; IrdabisantIUPAC/Chemical Name: (R)-6-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)pyridazin-3(2H)-oneInChi Key: XUKROCVZGZNGSI-CQSZACIVSA-NInChi Code: InChI=1S/C18H23N3O2/c1-14-4-2-11-21(14)12-3-13-23-16-7-5-15(6-8-16)17-9-10-18(22)20-19-17/h5-10,14H,2-4,11-13H2,1H3,(H,20,22)/t14-/m1/s1SMILES Code: O=C1C=CC(C2=CC=C(OCCCN3[C@H](C)CCC3)C=C2)=NN1Appearance: Solid powderPurity: >99% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: